发明名称 3,3 diphenyl prop-2-yl amino acid derivatives and their use as tachykinin antagonists
摘要 PCT No. PCT/GB93/02592 Sec. 371 Date Dec. 8, 1995 Sec. 102(e) Date Dec. 8, 1995 PCT Filed Dec. 17, 1993 PCT Pub. No. WO94/15903 PCT Pub. Date Jul. 21, 1994Compounds of formula (I), or a salt or prodrug thereof, wherein R1 represents H, C1-4alkyl or CH2COOH; R2 represents H or C1-4alkyl, with the proviso that R1 and R2 are not both H; R3 and R4 each independently rely resent H, C1-, alkyl. C2-6alkenyl C1-6alkoxy, halo or trifluoromethyl; A1, A2, A3, and A4each independently represent H, C1-6alkyl, C1-6alkenyl, C1-6alkoxy, halo or trifluoromethyl; and A5 and A6 each independently represent H or C1-4are tachykinin antagonists useful <IMAGE> (I)
申请公布号 AU5707294(A) 申请公布日期 1994.08.15
申请号 AU19940057072 申请日期 1993.12.17
申请人 MERCK SHARP & DOHME LIMITED 发明人 MARTIN RICHARD TEALL;BRIAN JOHN WILLIAMS
分类号 C07C229/14 主分类号 C07C229/14
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