摘要 |
PCT No. PCT/EP90/02250 Sec. 371 Date Aug. 2, 1991 Sec. 102(e) Date Aug. 2, 1991 PCT Filed Dec. 19, 1990 PCT Pub. No. WO91/08765 PCT Pub. Date Jun. 27, 1991.Stabilized compositions containing a non-glycosylated human tissue type plasminogen activator derivative are disclosed. The derivative is referred to as K2P pro. The composition has enzymatic activity of at least 1.1 mU/ml, a pH of from 4.5 to 6.5, and contains citrate as well as at least one of a variety of different compounds. |