| 摘要 |
A xanthine derivative of the formula (I): <IMAGE> (I) wherein R1 represents substituted or unsubstituted lower alkyl, lower alkenyl, lower alkynyl, substituted or unsubstituted alicyclic alkyl, substituted or unsubstituted phenyl, or substituted or unsubstituted benzyl; R2 represents -(CH2)m-X, wherein m is 2 or 3, and X is <IMAGE> wherein a is NH, O or S, b and d are the same or different and are CH or N, and R3 is lower alkyl, substituted or unsubstituted alicyclic alkyl, or substituted or unsubstituted phenyl, or <IMAGE> wherein e, g and h are the same or different and are CH or N, and R3 is the same as defined above; Q represents substituted or unsubstituted alicyclic alkyl,fferent and are substituted or unsubstituted alicyclic alkyl, <IMAGE> wherein Y is single bond or alkylene; and n is 0 or 1, <IMAGE> wherein K-M is -CH2-CH2-or -CH=CH-, and Y is the same as defined above, or <IMAGE> wherein Y is the same as defined above; or a pharmacologically acceptable salt thereof is disclosed. This derivative has anti-dementia activity.
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