POLYPEPTIDES HAVING AMIDASE ACTIVITY, GENETIC TOOLS AND HOST MICROORGANISMS FOR OBTAINING SAME

摘要

Novel polypeptides having amidase activity for hydrolyzing amides into carboxylates, and having a greater enzymatic activity for ammonium adipamate than for adipamide. A DNA sequence coding for a polypeptide having amidase activity for hydrolyzing amides into carboxylates, an analogue thereof resulting from genetic code degeneration, or a DNA sequence hybridizing with one of said sequences or a fragment thereof and coding for a polypeptide having amidase activity, are disclosed. Germs suitable for producing said polypeptides are also disclosed.