发明名称 Compositions containing argatroban analogs.
摘要 <p>An antithrombin composition in the form of a lipid emulsion which comprises, together with unsaturated fatty acid and an emulsifier, N&lt;2&gt;-arylsulfonyl-L-arginineamide of the following general formula (I): &lt;CHEM&gt; wherein R&lt;1&gt; represents (2R,4R)-4-alkyl-2-carboxypiperidino group, R&lt;2&gt; represents phenyl group or condensed polycyclic compound residue as defined below, said R&lt;2&gt; optionally having one or more substituents selected from lower alkyl group, lower alkoxy group, or amino group substituted by lower alkyl group, said condensed polycyclic compound residue being a condensed polycyclic compound residue including a benzene ring, said benzene ring being bound to the sulfur atom of the sulfonyl group in the general formula (I), and said benzene ring being condensed with other ring which may be a heterocyclic ring, and said polycyclic compound residue having 7 - 14 carbon atoms in total, its hydrate and/or its salt is provided.</p>
申请公布号 EP0608828(A1) 申请公布日期 1994.08.03
申请号 EP19940101051 申请日期 1994.01.25
申请人 MITSUBISHI KASEI CORPORATION 发明人 IGAKI, MATSUO
分类号 A61K9/107;A61K9/00;A61K31/445;A61K31/47;A61K47/12;A61K47/14;A61K47/24;A61P7/02;(IPC1-7):A61K31/47 主分类号 A61K9/107
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