| 摘要 |
PCT No. PCT/US91/04352 Sec. 371 Date Feb. 22, 1993 Sec. 102(e) Date Feb. 22, 1993 PCT Filed Jun. 26, 1991.There are disclosed preparative processes and hypoglycemic compounds of the formula <IMAGE> wherein R is hydrogen or C1 to C3 alkyl; R1 and R2 are taken together and are carbonyl; or R1 and R2 are taken separately, wherein R1 is hydrogen or R4 and R2 is-COR5 and COOR5; R3, R4 and R5 are each independently C1 to C9 alkyl, C3 to C7 cycloalkyl, phenyl, naphthyl, furyl, benzofuryl or thienyl or one of said groups mono- or disubstituted with C1 to C3 alkyl, C1 to C3 alkoxy, C1 to C3 alkoxy-carbonyl, trifluoromethyl, fluoro or chloro; and n is 0 or 1; or pharmaceutically acceptable cationic salts thereof.
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