发明名称 |
CARBAPENEM, ANTIBACTERIAL PHARMACEUTICAL COMPOSITION CONTAINING CARBAPENEM, ITS PRODUCTION, AND INTERMEDIATE THEREFOR |
摘要 |
The present invention provides a compound of the formula: <IMAGE> (I) or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof wherein: A is a group of the formula (IA) or (IB): <IMAGE> (IA) <IMAGE> (IB) R1 is 1-hydroxyethyl, 1-fluoroethyl or hydroxymethyl; R2 is hydrogen or C1-4alkyl; R3 and R4 are the same or different and are a variety of substituents X is alkanediyl containing 1-6 carbon atoms optionally interrupted by O, S(O)x (wherein x is zero, one or two), -CONR5- or -NR5- or wherein R5 is hydrogen or C1-4alkyl; or X is alkenediyl containing 1-6 carbon atoms optionally interrupted by O, S(O)x or -NR5-. |
申请公布号 |
JPH06211860(A) |
申请公布日期 |
1994.08.02 |
申请号 |
JP19930241519 |
申请日期 |
1993.09.28 |
申请人 |
ZENEKA LTD;ZENEKA PHARMA SA |
发明人 |
MAIKERU JIYON BETSUTSU;GARESU MOOSU DEIBUIIZU;FUREDERIKU ANRI YUNGU |
分类号 |
A61K31/40;A61K31/397;A61P31/04;C07D205/08;C07D207/16;C07D403/12;C07D409/12;C07D409/14;C07D477/00;C07D477/20;C07F9/568 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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