发明名称 |
Platelet receptor antagonists useful in detecting intravascular platelet aggregation |
摘要 |
This invention provides novel compounds used in a method of determining platelet deposition. These compounds include 123I-SAP and analogues. Also provided is a method of determining platelet deposition in a subject comprising binding an effective radiolabeled platelet receptor antagonist with a platelet, allowing sufficient time for the platelet to migrate within the subject, and visualizing the radiolabeled platelet in the subject.
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申请公布号 |
US5334369(A) |
申请公布日期 |
1994.08.02 |
申请号 |
US19910713726 |
申请日期 |
1991.06.11 |
申请人 |
MEDICAL UNIVERSITY OF SOUTH CAROLINA |
发明人 |
HALUSHKA, PERRY V.;SPICER, KEN M.;MAIS, DALE E. |
分类号 |
A61K49/04;A61K31/557;A61K51/04;C07C311/19;C07C311/20;C07C405/00;C07D493/08;(IPC1-7):A61K49/02 |
主分类号 |
A61K49/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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