| 摘要 |
New therapeutic agent of carboxymethylidenecycloheptimidazole derivatives and method for the manufacture thereof are disclosed, which are represented by the following formula or its alkali addition salts <IMAGE> (1) (wherein R1 represents a lower alkyl; R2 represents H or isopropyl group; R3 represent H, a lower alkyl or -C(CH3)H-OCOOR4 (R4 is a lower alkyl or cyclohexyl) and =CHCOOR3 is substituted group at 4 or 8 position; A represents <IMAGE> These compounds are useful as anti-hypertensive, anti-congestive heart failure agents and intraocular pressure lowering agents. |
