| 发明名称 |
PENTACYCLIC TRITERPENOID COMPOUNDS AS TOPOISOMERASE INHIBITORS OR CELL DIFFERENTIATION INDUCERS |
| 摘要 |
Pentacyclic triterpenoid compounds such as .alpha.-boswellic acid and its acetate, .beta.-boswellic acid and its acetate, which have an inhibitory effect on topoisomerase I and topoisomerase II, are disclosed. Compositions based on the pentacyclic triterpenoid compounds which can be used to treat various cancers in mammals are also disclosed.
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| 申请公布号 |
CA1330944(C) |
申请公布日期 |
1994.07.26 |
| 申请号 |
CA19890608654 |
申请日期 |
1989.08.17 |
| 申请人 |
RESEARCH TRIANGLE INSTITUTE |
发明人 |
LEE, YUE-WEI;FANG, OI-CHENG;WANG, ZHEN-GUO;LI, DE-HUA;COOK, C. EDGAR |
| 分类号 |
A61K31/16;A61K31/18;A61K31/19;A61K31/195;A61K31/215;A61K31/235;A61K31/70;A61K31/7028;A61K31/7034;A61K31/704;A61P31/12;A61P35/00;A61P35/02;A61P43/00;C07C62/06;C07C69/00;C07C69/145;C07H15/256;(IPC1-7):A61K31/56;A61K31/165;A61K31/21 |
主分类号 |
A61K31/16 |
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