发明名称 BLOCK COPOLYMER-MEDICINAL AGENT COMPOSITE AND BLOCK COPOLYMER
摘要 PURPOSE:To provide a block copolymer-medicinal agent composite improved in the solubility of the medicinal agent sparingly soluble in water, and having such high pharmacological effect as not to be found in the medicinal agent, and to provide a block copolymer to be used for the composite. CONSTITUTION:The composite characterized by that a block copolymer made up of (A) hydrophilic polymer structural portions and (B) hydrophobic polymer structural portions to which no medicinal agent has not been bound, bearing anthracene skeleton and/or anthraquinone skeleton in the side chain, forms micelles with the portions A as the outer nucleus and a sparingly water-soluble medicinal agent is included in the hydrophobic inner nucleus.
申请公布号 JPH06206830(A) 申请公布日期 1994.07.26
申请号 JP19930261126 申请日期 1993.10.19
申请人 NIPPON KAYAKU CO LTD;SAKURAI YASUHISA;RES DEV CORP OF JAPAN 发明人 YOKOYAMA MASAYUKI;KATAOKA KAZUNORI;OKANO MITSUO;SAKURAI YASUHISA;SETO TAKASHI;FUKUSHIMA SHIGETO;MACHIDA MEGUMI;YOKUMOTO HISAO;OKAMOTO KAZUYA;MASHIBA YOKO
分类号 A61K9/107;A61K31/70;A61K31/765;A61K45/00;A61K47/34;A61P35/00;C08G65/32 主分类号 A61K9/107
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