发明名称 |
BLOCK COPOLYMER-MEDICINAL AGENT COMPOSITE AND BLOCK COPOLYMER |
摘要 |
PURPOSE:To provide a block copolymer-medicinal agent composite improved in the solubility of the medicinal agent sparingly soluble in water, and having such high pharmacological effect as not to be found in the medicinal agent, and to provide a block copolymer to be used for the composite. CONSTITUTION:The composite characterized by that a block copolymer made up of (A) hydrophilic polymer structural portions and (B) hydrophobic polymer structural portions to which no medicinal agent has not been bound, bearing anthracene skeleton and/or anthraquinone skeleton in the side chain, forms micelles with the portions A as the outer nucleus and a sparingly water-soluble medicinal agent is included in the hydrophobic inner nucleus. |
申请公布号 |
JPH06206830(A) |
申请公布日期 |
1994.07.26 |
申请号 |
JP19930261126 |
申请日期 |
1993.10.19 |
申请人 |
NIPPON KAYAKU CO LTD;SAKURAI YASUHISA;RES DEV CORP OF JAPAN |
发明人 |
YOKOYAMA MASAYUKI;KATAOKA KAZUNORI;OKANO MITSUO;SAKURAI YASUHISA;SETO TAKASHI;FUKUSHIMA SHIGETO;MACHIDA MEGUMI;YOKUMOTO HISAO;OKAMOTO KAZUYA;MASHIBA YOKO |
分类号 |
A61K9/107;A61K31/70;A61K31/765;A61K45/00;A61K47/34;A61P35/00;C08G65/32 |
主分类号 |
A61K9/107 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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