发明名称 |
DETECTION OF DNA CONTAMINANTS BY PCR |
摘要 |
A method for detecting the presence of small mounts of contaminant DNA, present in an amount of at least about 0.1 picogram of DNA, in a protein product produced by recombinant DNA technology. The method comprises using oligonucleotides with sequences directed to those of repetitive host cell line DNA sequences, as primers in a PCR reaction. Also disclosed are kits for the detection of small amounts of contaminant DNA in a protein product. |
申请公布号 |
WO9412669(A3) |
申请公布日期 |
1994.07.21 |
申请号 |
WO1993US11582 |
申请日期 |
1993.11.30 |
申请人 |
GENETICS INSTITUTE, INC. |
发明人 |
LETWIN, BRUCE, W.;JEZUIT, MELISSA, A. |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|