发明名称 |
PROCESS FOR PRODUCING M-CSF 223 |
摘要 |
DNA molecules which encode a 255 amino acid polypeptide, comprising the 32 amino acid M-CSF leader sequence and the 223 amino acid mature M-CSF polypeptide, and lack the coding sequence for the carboxy-terminal propeptide sequence present in wild-type M-CSF DNA, result in highly efficient production of M-CSF, which displays similar post-translational modifications as wild-type M-CSF and is unaffected in biological properties. |
申请公布号 |
WO9416075(A2) |
申请公布日期 |
1994.07.21 |
申请号 |
WO1994US00658 |
申请日期 |
1994.01.12 |
申请人 |
GENETICS INSTITUTE, INC. |
发明人 |
DORNER, ANDREW;FRITSCH, EDWARD, F.;STEININGER, ROBERT;BUSH, LAWRENCE |
分类号 |
C12N15/09;A61K38/00;C07K1/16;C07K1/34;C07K14/53;C12N5/10 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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