发明名称 AMINO ACIDS AND PEPTIDES HAVING MODIFIED TERMINALS
摘要 Compounds which have one of structural formulae (I) or (II). AA is an amino acid residue or an amino acid chain of two or more amino acid residues, excluding the N-terminal and the C-terminal from said amino acid residue or amino acid chain of two or more amino acid residues; R1 is hydrogen or an alkyl group having from 1 to 8 carbon atoms; R2 is selected from the group consisting of (i) a substituted or unsubstituted hydrocarbon having from 1 to 20 carbon atoms, and (ii) (a). R4 is an aliphatic hydrocarbon having 1 to 4 carbon atoms. R4 may be substituted or unsubstituted. R3 is selected from the group consisting of (i) hydrogen; (ii) (b), wherein R5 is hydrogen or a nitro group; and (iii) (c), wherein each of R6, R7, and R8 is hydrogen or methyl. The above compounds are useful as pharmaceuticals for inhibiting the growth of target cells, viruses, or virally-infected cells.
申请公布号 WO9415909(A1) 申请公布日期 1994.07.21
申请号 WO1994US00335 申请日期 1994.01.11
申请人 MAGAININ PHARMACEUTICALS, INC. 发明人 KARI, U., PRASAD
分类号 A61K38/00;A61K31/16;A61K31/165;A61P31/00;A61P31/04;A61P31/12;A61P33/00;C07C237/20;C07C237/22;C07C279/10;C07C279/12;C07C279/14;C07C279/18;C07C279/34;C07C279/36;C07K5/023;C07K5/027;C07K5/065;C07K5/068;C07K5/083;C07K5/09;C07K5/093;C07K5/11;(IPC1-7):C07C279/04;C07C233/03;C07C271/00;A61K31/27;A61K31/195;A61K37/02 主分类号 A61K38/00
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