| 发明名称 |
N-METHYLDEACETYLCOLCHICEINAMIDE DERIVATIVES |
| 摘要 |
N-methyldeacetylcolchiceinamide derivatives represented by the formula wherein R denotes a residue obtained by removing COOH from a C3-C7 sugar carboxylic acid, and hydroxyl groups present in the residue may properly be protected with a protecting group for a hydroxyl group. Said N-methyldeacetylcolchiceinamide derivatives have less toxicity and strong effect for inhibiting proliferation of tumor cells, and are expected to be used as a carcinostatic.
|
| 申请公布号 |
CA2094796(A1) |
申请公布日期 |
1994.07.21 |
| 申请号 |
CA19932094796 |
申请日期 |
1993.04.23 |
| 申请人 |
OHGEN RESEARCH LABORATORIES LTD. |
发明人 |
AKIYAMA, KIYOSHI |
| 分类号 |
A61K31/335;A61K31/165;A61K31/357;A61K31/70;A61K31/7012;A61K31/704;A61P35/00;C07C233/32;C07C235/14;C07D317/32;C07H7/033;C07H7/06;(IPC1-7):C07D317/32;C07H7/02;A61K31/16 |
主分类号 |
A61K31/335 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
