发明名称 NEW ZOANTHAMINE DERIVATIVE
摘要 <p>PURPOSE:To obtain the subject new compounds, capable of manifesting in vitro inhibiting activity against the proliferation of a cancerous cell P388 and useful as an antitumor agent. CONSTITUTION:This compounds of formulas I to III (R is H or OH-protecting group), e.g. cyclozoanthamine of formula IV. The compounds of formulas I to III are obtained by pulverizing a coelenterate, e.g. a zoanthidean polyp of the genus Zoanthus in an organic solvent, extracting the compounds therefrom and further separating the extracted compounds by chromatography.</p>
申请公布号 JPH06199867(A) 申请公布日期 1994.07.19
申请号 JP19930083887 申请日期 1993.03.19
申请人 SAGAMI CHEM RES CENTER 发明人 KAMIMURA DAISUKE;NAGATSU AKITO;YAMADA KAORU
分类号 A61K31/435;A61P35/00;C07D498/22;(IPC1-7):C07D498/22 主分类号 A61K31/435
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