| 摘要 |
Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising a polymeric material capable of forming a coating on the gastrointestinal tract and an x-ray producing agent of the formula <IMAGE> and methods for their use in diagnostic radiology of the gastrointestinal tract wherein Z=H, halo, C1-C20 alkyl, cycloalkyl, lower alkoxy, cyano, where the alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups; R1 and R2 are independently H, C1-C25 alkyl, cycloalkyl acetyl, or halo-lower-alkyl, wherein said C1-C25 alkyl, cycloalkyl, acetyl and halo-lower-alkyl are optionally substituted with, fiuoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxy-carbonyloxy; n is 1-5; y is 1-4; and x is 1 or 2 in a pharmaceutically acceptable carrier.
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