摘要 |
SALTS OF 4-PYRIMIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION Alkanolamine salts and basic amino acid salts of derivatives which may exist in three tautomeric forms of formulae (I), (I'), and (I'') <IMG> <IMG> <IMG> (I) (I') (I'') in which R1 represents a linear or branched (C1-C7)alkyl group, R2 represents either an aryl(C1-C3)alkyl group optionally substituted on the nucleus, or a heteroaryl(C1-C3)alkyl group optionally substituted on the nucleus and, R3 represents either a COOH group, or a 1H-tetrazol-5-yl group, are useful in therapy as antagonists of angiotensin II.
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