发明名称 SALTS OF 4-PYRIMIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
摘要 SALTS OF 4-PYRIMIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION Alkanolamine salts and basic amino acid salts of derivatives which may exist in three tautomeric forms of formulae (I), (I'), and (I'') <IMG> <IMG> <IMG> (I) (I') (I'') in which R1 represents a linear or branched (C1-C7)alkyl group, R2 represents either an aryl(C1-C3)alkyl group optionally substituted on the nucleus, or a heteroaryl(C1-C3)alkyl group optionally substituted on the nucleus and, R3 represents either a COOH group, or a 1H-tetrazol-5-yl group, are useful in therapy as antagonists of angiotensin II.
申请公布号 CA2113491(A1) 申请公布日期 1994.07.16
申请号 CA19942113491 申请日期 1994.01.14
申请人 SYNTHELABO 发明人 HOORNAERT, CHRISTIAN;WICK, ALEXANDER E.;WICK ALEXANDER E
分类号 A61K31/44;A61K31/4427;A61K31/505;A61P9/12;A61P27/02;A61P27/06;A61P43/00;C07D239/36;C07D257/04;C07D401/04;C07D401/14;C07D403/10;(IPC1-7):C07D403/10 主分类号 A61K31/44
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