| 发明名称 |
Carbohydrate-directed cross-linking reagents |
| 摘要 |
The invention is from the field of heterobifunctional cross-linking reagents. More particularly, the invention concerns cross-linking reagents which combine a nucleophilic hydrazide residue with an electrophilic maleimide residue, thereby allowing coupling of aldehydes to free thiols.
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| 申请公布号 |
US5329028(A) |
申请公布日期 |
1994.07.12 |
| 申请号 |
US19920926077 |
申请日期 |
1992.08.05 |
| 申请人 |
GENENTECH, INC. |
发明人 |
ASHKENAZI, AVI J.;CHAMOW, STEVEN M.;KOGAN, TIMOTHY P. |
| 分类号 |
C07D207/44;C07D207/452;C07K1/107;C07K14/805;(IPC1-7):C07D207/452 |
主分类号 |
C07D207/44 |
| 代理机构 |
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| 地址 |
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