发明名称 IMPROVED METHODS FOR THE DETERMINATION AND ADJUSTMENT OF PROLACTIN DAILY RHYTHMS
摘要 A method for detecting abnormalities in prolactin daily rhythms. The method includes the step of comparing a prolactin profile of the test subjects over a predetermined period to a predetermined standard prolacting profile of healthy subjects. The method also includes the step of determining whether the test subjects have an abnormal daily prolacting rhythm by ascertaining the prolactin level during waking hours and sleeptime. The determination is made to see if the test subjects have a prolactin level that is greater than 1 SEM above the normal prolactin profile of healthy subjects at waking hours and at sleep time, a prolactin level that is at least one SEM lower than the normal prolactin profile of the healthy subjects. Methods are also provided for determining adjustments needed to an abnormal prolactin profile to cause it to conform to the prolactin profile of a healthy subject.
申请公布号 WO9415211(A1) 申请公布日期 1994.07.07
申请号 WO1993US12701 申请日期 1993.12.22
申请人 ERGO SCIENCE INCORPORATED;BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY 发明人 MEIER, ALBERT, H.;CINCOTTA, ANTHONY, H.
分类号 A61K31/00;A61K31/13;A61K31/137;A61K31/15;A61K31/166;A61K31/195;A61K31/221;A61K31/35;A61K31/352;A61K31/40;A61K31/405;A61K31/435;A61K31/439;A61K31/445;A61K31/4515;A61K31/454;A61K31/46;A61K31/475;A61K31/48;A61K31/54;A61K31/5415;A61K31/55;A61K31/551;A61K31/5513;A61K31/695;A61K38/22;A61K45/06;G01N33/74;(IPC1-7):G01N33/00 主分类号 A61K31/00
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