发明名称 |
HYDANTOIN AND SUCCINIMIDE-SUBSTITUTED DERIVATIVES OF SPIROINDANYLCAMPHORSULFONYL OXYTOCIN ANTAGONISTS |
摘要 |
Compounds of formula (I) where X is (a) or (b), R is Het, wherein Het is as defined in the description. These compounds are oxytocin and vasopressin antagonists useful in the treatment of preterm labor, dysmenorrhea, and for the stoppage of labor preparatory to cesarean delivery, timing of parturition, uterine hyperactivity, endometriosis, hypertension, congestive heart failure, hyponatremia and cognitive disorders.
|
申请公布号 |
CA2151821(A1) |
申请公布日期 |
1994.07.07 |
申请号 |
CA19932151821 |
申请日期 |
1993.12.23 |
申请人 |
MERCK & CO., INC. |
发明人 |
GILBERT, KEVIN;HOBBS, DOUG W.;VEBER, DANIEL F.;WILLIAMS, PETER D.;EVANS, BEN E. |
分类号 |
C07D295/22;A61K31/4427;A61K31/443;A61K31/445;A61K31/495;A61P13/02;A61P15/00;C07D207/27;C07D207/273;C07D207/40;C07D207/416;C07D221/20;C07D295/26;C07D401/12;C07D401/14;C07D403/14;C07D405/06;C07D405/14;C07D471/10;C07D487/04;C07D498/04;C07F9/6558;(IPC1-7):C07D401/12;A61K31/435;A61K31/535;A61K31/54;C07F9/655;A61K31/675 |
主分类号 |
C07D295/22 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|