COPOLYMER-BASED FILMS, APPLICATIONS THEREOF IN TRANSDERMAL SYSTEMS AND PROCESSES FOR THEIR PREPARATION

摘要

Copolymer-based films, applications thereof in transdermal systems and processes for their preparation. Said films consist of a vinyl ethylene/acetate type hydrophobic polymer containing at least one active principle and including 15 to 50 % hydrophilic inclusions formed from at least one hydrophilic monomer selected from the group comprising acrylamide, methylol acrylamide, diacetone acrylamide, maleic acid, acrylic acid, fumaric acid, itaconic acid, propylene glycol acrylate, ethylene glycol methacrylate, methacrylamide, methacrylic acid, propylene glycol methacrylate, hydroxyethyl methacrylate, dimethylaminoethyl methacrylate, N-vinylpyrrolidone, vinylacetic acid, vinylsulfonic acids.