发明名称 |
Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants |
摘要 |
The present invention is directed to a composition comprised of nanoparticles containing an X-ray diagnostic compound, having a high molecular weight nonionic surfactant as a surface modifier adsorbed on the surface thereof and a cloud point modifier associated therewith. The present invention is still further directed to a method for diagnostic imaging for use in medical procedures comprising administering to the body of a test subject in need of an X-ray an effective contrast producing amount of a composition comprised of nanoparticles containing an X-ray diagnostic compound, having a high molecular weight nonionic surfactant as a surface modifier adsorbed on the surface thereof and a cloud point modifier associated therewith.
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申请公布号 |
US5326552(A) |
申请公布日期 |
1994.07.05 |
申请号 |
US19920991909 |
申请日期 |
1992.12.17 |
申请人 |
STERLING WINTHROP INC. |
发明人 |
NA, GEORGE C.;RAJAGOPALAN, NATARAJAN |
分类号 |
A61K49/04;(IPC1-7):A61K49/04;A61K9/14;A61K9/50 |
主分类号 |
A61K49/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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