MICROBIOLOGICAL METHOD FOR HYDROXYLATING ETHYL GROUP OF FIVE- OR SIX-MEMBERED RING OF AROMATIC HETEROCYCLIC COMPOUND AT TERMINAL PORTION THEREOF

摘要

A microbiological process for the terminal hydroxylation of ethyl groups on aromatic 5- or 6-membered heterocycles is described. The hydroxylation is carried out with microorganisms which a) contain the genes of a Pseudomonas OCT plasmid which form an active alkane monooxygenase and b) form no active chromosomal- or plasmid-encoded alcohol dehydrogenase. i