| 发明名称 |
Diaryl 5,6-fusedheterocyclic acids as leukotriene antagonists. |
| 摘要 |
<p>Compounds having the formula I: <CHEM> are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and ollograft rejection.</p> |
| 申请公布号 |
EP0604114(A1) |
申请公布日期 |
1994.06.29 |
| 申请号 |
EP19930310127 |
申请日期 |
1993.12.15 |
| 申请人 |
MERCK FROSST CANADA INC. |
发明人 |
YOUNG, ROBERT N.;XIANG, YI BIN;LABELLE, MARC;LAU, CHEUK K.;LEBLANC, YVES;DUFRESNE, CLAUDE;GAREAU, YVES |
| 分类号 |
A61K31/437;C07D491/04;C07D491/048;C07D495/04;C07D513/04;(IPC1-7):C07D495/04;A61K31/44 |
主分类号 |
A61K31/437 |
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