METHOD OF PRODUCING ALPHA-HYDROXYISOBUTYLAMIDE

摘要

A culture liquid of microorganisms having an ability of producing alpha -hydroxyisobutylamide from acetone cyanhydrin or the cultivated cells of the microorganisms or the processed cells of them is/are reacted to acetone cyanhydrin in an aqueous medium to produce alpha -hydroxyisobutylamide. The amide is reacted with water and/or an aliphatic alcohol in the presence of a solid acid catalyst at a temperature of 150 DEG C or higher in a gaseous phase or a gaseous-liquid mixed phase to produce an alpha , beta -unsaturated carboxylate or an aliphatic alcohol or an alpha , beta -unsaturated carboxylic acid.