发明名称 3-(Quinolin-6-yl-methyl)-4H-imidazol-4-one derivatives as angiotensin II antagonists.
摘要 3-(Quinol-6-ylmethyl)-4H-imidazol-4-one derivatives corresponding to the formula (I) <IMAGE> in which R1 represents a straight or branched (C2-C5)alkyl group, R2 and R3 represent, each independently of the other, either a hydrogen atom, or a straight or branched (C1-C5)alkyl group, or a group (CH2)n-aryl where n = 0 to 3, or R2 and R3 can form, with the imidazole ring, a spirocyclo(C3-C8)alkyl group, and their addition salts with pharmaceutically acceptable acids and bases. Therapeutic application.
申请公布号 EP0604259(A1) 申请公布日期 1994.06.29
申请号 EP19930402949 申请日期 1993.12.07
申请人 SYNTHELABO 发明人 CREMER, GERARD;MULLER, JEAN-CLAUDE
分类号 A61K31/47;A61P9/00;A61P9/12;A61P11/00;A61P13/02;A61P15/00;A61P27/02;A61P27/06;A61P43/00;C07D215/12;C07D233/70;C07D235/02;C07D257/04;C07D401/14 主分类号 A61K31/47
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