| 摘要 |
PURPOSE:To reduce the amount of a catalyst used and efficiently obtain an N-(alpha-alkoxyethyl)formamide good in thermal stability by regulating diformamide in formamide used as a raw material to a prescribed content or below, then reacting the prepared formamide with acetaldehyde and further reacting the resultant compound with an alcohol. CONSTITUTION:Formamide is made to react with acetaldehyde in the presence of a basic catalyst to provide N-(alpha-hydroxyethyl)formamide, which is then allowed to react with a primary or a secondary alcohol in the presence of an acidic catalyst to afford an N-(alpha-alkoxyethyl)formamide. Formamide with <=1000 wt.ppm, preferably <=500wt.ppm content of the diformamide in the formamide is used as the raw material. Furthermore, acetaldehyde with $ 300 wt. ppm content of acetic acid is preferably used as the raw material. The formamide purified by vacuum distillation using a column is especially preferably used as the raw material. The N-(alpha-alkoxyethyl)formamide obtained by this method is preferably purified by the vacuum distillation using a column. |
