发明名称 |
Dibenzothiazepine derivatives useful as antispasmodic agents. |
摘要 |
<p>The invention provides compounds of the formula:- <CHEM> wherein k is 1, 2 or 3; m is 1, 2 or 3; n is 1, 2 or 3; p is 0, 1 or 2; X is O, S or a direct link, with the proviso that when X is O or S, n is 2 or 3; R<1> is H or C1-C4 alkyl; and R<2> is an optionally substituted phenyl or heteroaryl group; and pharmaceutically acceptable salts thereof. These compounds are useful for the treatment of motility disorders, particularly those of the gut such as irritable bowel syndrome.</p> |
申请公布号 |
EP0404359(B1) |
申请公布日期 |
1994.06.29 |
申请号 |
EP19900305718 |
申请日期 |
1990.05.25 |
申请人 |
PFIZER LIMITED;PFIZER INC. |
发明人 |
ALKER, DAVID, DR.;BASS, ROBERT J., DR.;CROSS, PETER EDWARD, DR. |
分类号 |
A61K31/55;C07D;C07D207/09;C07D417/06;C07D417/14;(IPC1-7):C07D417/06;C07D409/06;A61K31/35;C07D403/06;C07D405/06;C07D211/26 |
主分类号 |
A61K31/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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