发明名称 |
Azole derivatives, pharmaceutical compositions containing the same, and method for treating mycosis and estrogen-dependent diseases |
摘要 |
Azole derivatives (including stereoisomers and pharmaceutically acceptable salts) of the formula: C4 alkyl; R3 is H, OH, CN, halogen, haloalkyl, C1-C4 alkyl or phenyl, and if there are two or more R3 groups, such R3 groups may be the same or different; n is an integer from 0 to 5; Y is N or CH; and X is O, S or NH have antimycotic and aromatase inhibitory activities. Compositions containing the azole derivatives and a method of treating mycosis and estrogen-dependent diseases by administering effective quantities of the azole derivatives are also disclosed.
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申请公布号 |
US5324740(A) |
申请公布日期 |
1994.06.28 |
申请号 |
US19930067052 |
申请日期 |
1993.05.26 |
申请人 |
KUREHA CHEMICAL INDUSTRY CO., LTD. |
发明人 |
NIIMURA, KOICHI;IKEDA, YUKO;KATO, AKIRA;ANDO, TAKAO |
分类号 |
A61K31/41;A61K31/415;A61P31/04;A61P31/10;A61P35/00;A61P43/00;C07D249/08;C07D307/33;C07D333/38;C07D403/06;C07D405/06;C07D409/06;C07D493/10;C07D495/10;C07D521/00;(IPC1-7):A61K31/415 |
主分类号 |
A61K31/41 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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