ANTIRETROVIRAL HYDRAZINE DERIVATIVES

摘要

Antiretroviral Hydrazine Derivatives Compounds of formula <IMG> (I), wherein R1 and R9 are each independently of the other hydrogen; acyl; unsubstituted or substituted alkyl; sulfo; or sulfonyl substituted by unsubstituted or substituted alkyl, aryl or by heterocyclyl, with the proviso that not more than one of the radicals R1 and R9 is hydrogen; and R2 and R8 are each independently of the other hydrogen or unsubstituted or substituted alkyl; R3 and R4 are each independently of the other hydrogen, unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl or aryl; R5 is acyloxy; R6 is hydrogen; and R7 is unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl or aryl; and salts of the mentioned compounds where salt-forming groups are present, are described; those compounds exhibit antiretroviral activity.