ANTIALLERGIC TRIAZOLOBENZAZEPINE DERIVATIVES

摘要

Antiallergic triazolobenzazepines of formula (I), wherein each of the dotted lines independently represents an optional bond; R<1> represents hydrogen, halo, c1-4alkyl, hydroxy or C1-4alkyloxy; R<2> represents hydrogen, halo, C1-4alkyl, hydroxy or C1-4alkyloxy; R<3> represents hydrogen, C1-4alkyl or halo; -B D- is a bivalent radical of formula -C(R<4>) N- (a-1); or -N C(R<5>)- (a-2); R<4> and R<5> represent hydrogen, C1-4alkyl, ethenyl substituted with hydroxycarbonyl or C1-4alkyloxycarbonyl, C1-4alkyl substituted with hydroxycarbonyl or C1-4alkyloxycarbonyl, hydroxyC1-4alkyl, formyl or hydroxycarbonyl; R<5> also represents phenyl or pyridinyl; L represents hydrogen; C1-6alkyl; substituted C1-6alkyl, C3-6alkenyl; C3-6alkenyl substituted with aryl or, L represents a radical of formula -Alk-Y-Het<1> (b-1), -Alk-NH-CO-Het<2> (b-2) or -Alk-Het<3> (b-3). Compositions comprising said compounds, processes of preparing the same, and intermediates in the preparation thereof.