发明名称 CLOTTING INHIBITOR MADE FROM PROTOSTOMIA SALIVA
摘要 The invention relates to a natural or synthetically producible protein which acts as a clotting inhibitor and can be isolated from the saliva of insects which suck mammals' blood. The preferred insect is Triatoma pallidipennis. The protein is used in the treatment of thrombosis or unstable angina or arteriosclerosis or to prevent vessels from re-closing after PTCA/PTA or to prevent blood from coagulating in haemodialysis.
申请公布号 WO9413807(A1) 申请公布日期 1994.06.23
申请号 WO1993DE01172 申请日期 1993.12.03
申请人 SCHERING AKTIENGESELLSCHAFT;NOESKE-JUNGBLUT, CHRISTIANE;SCHLEUNING, WOLF-DIETER;ALAGON, ALEJANDRO;POSSANI, LOURIVAL;CUEVAS-AGUIERRE, DELIA;DONNER, PETER;HAENDLER, BERNARD;HECHLER, ULRIKE 发明人 NOESKE-JUNGBLUT, CHRISTIANE;SCHLEUNING, WOLF-DIETER;ALAGON, ALEJANDRO;POSSANI, LOURIVAL;CUEVAS-AGUIERRE, DELIA;DONNER, PETER;HAENDLER, BERNARD;HECHLER, ULRIKE
分类号 C12N15/09;A61K35/12;A61K35/56;A61K35/64;A61K38/00;A61K38/55;A61K38/57;A61P7/02;A61P9/10;C07H21/04;C07K1/14;C07K14/435;C07K14/81;C12N1/21;C12N5/10;C12N9/99;C12N15/15;C12P21/00;C12P21/02;(IPC1-7):C12N15/15;A61K37/64;C07K13/00;C07K15/08 主分类号 C12N15/09
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