| 摘要 |
<p>Antiallergic triazolobenzazepines of formula (I), wherein each of the dotted lines independently represents an optional bond; R1 represents hydrogen, halo, c¿1-4?alkyl, hydroxy or C1-4alkyloxy; R?2¿ represents hydrogen, halo, C¿1-4?alkyl, hydroxy or C1-4alkyloxy; R?3¿ represents hydrogen, C¿1-4?alkyl or halo; -B$(1,3)$D- is a bivalent radical of formula -C(R?4¿)$(1,3)$N- (a-1); or -N$(1,3)$C(R5)- (a-2); R?4 and R5¿ represent hydrogen, C¿1-4?alkyl, ethenyl substituted with hydroxycarbonyl or C1-4alkyloxycarbonyl, C1-4alkyl substituted with hydroxycarbonyl or C1-4alkyloxycarbonyl, hydroxyC1-4alkyl, formyl or hydroxycarbonyl; R?5¿ also represents phenyl or pyridinyl; L represents hydrogen; C¿1-6?alkyl; substituted C1-6alkyl, C3-6alkenyl; C3-6alkenyl substituted with aryl or, L represents a radical of formula -Alk-Y-Het?1¿ (b-1), -Alk-NH-CO-Het2 (b-2) or -Alk-Het3 (b-3). Compositions comprising said compounds, processes of preparing the same, and intermediates in the preparation thereof.</p> |
