ANTIALLERGIC TRIAZOLO(PYRROLO, THIENO OR FURANO)AZEPINE DERIVATIVES

摘要

Antiallergic triazolo(pyrrolo, thieno or furano)azepines of formula (I), the pharmaceutically acceptable addition salts and stereochemically isomeric forms thereof, wherein each of the dotted lines independently represents an optional bond; -E-G-is a bivalent radical of formula -X-C(R1) CH (a-1); or -CH C(R2)-X- (a-2); X represents O, S or NR3; R3 represents hydrogen, C1-6alkyl or C1-4alkylcarbonyl, -B D- is a bivalent radical of formula -C(R4) N- (b-1); or -N C(R5)- (b-2); L represents hydrogen; C1-6alkyl; substituted C1-6alkyl; C3-6alkenyl; C3-6alkenyl substituted with aryl; or, L represents a radical of formula -Alk-Y-Het1 (c-1), -Alk-NH-CO-Het2 (c-2) or -Alk-Het3 (c-3). Compositions comprising said compounds, processes of preparing the same and intermediates in the preparation thereof.