发明名称 BENZOCYCLOHEPTENES, BENZOXEPINES AND BENZOTHIEPINES
摘要 2129642 9413658 PCTABS00032 The subject of the invention is compounds of general formula (I), in which: X represents O or CHR; R1, R2, R3 and R4, which are identical or different, represent a hydrogen atom or a C1-C7 alkyl group, it being possible for R1 to additionally form a bond with R; R5 represents a hydrogen atom, a hydroxyl group or R5, taken together with R7, forms a bond or a $(1,3)$O group; R6 represents a group of formula (a) in which R10 and R11, taken together with the carbon atom to which they are attached, form a nitrogenous heterocyclic group, and their N-oxides and pharmaceutically acceptable salts. These compounds are powerful activators of potassium channels.
申请公布号 CA2129642(A1) 申请公布日期 1994.06.23
申请号 CA19932129642 申请日期 1993.12.07
申请人 发明人 BERTHELON, JEAN-JACQUES;BRUNET, MICHEL;NOBLET, MARC;DURBIN, PHILIPPE;GUERRIER, DANIEL;LUONG, TRONG NGHIA
分类号 C07D215/14;A61K31/355;A61K31/55;A61P9/08;A61P9/10;A61P11/00;A61P11/08;A61P17/00;A61P21/02;A61P25/02;C07C57/30;C07C59/68;C07D213/24;C07D213/30;C07D213/57;C07D213/60;C07D213/89;C07D313/08;C07D405/04;C07D409/04;C07D493/04;(IPC1-7):C07D405/04;C07D217/14;C07C323/20;C07D239/26;A61K31/435;A61K31/495;C07C57/58;C07D215/60;C07C59/66 主分类号 C07D215/14
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