发明名称 |
HUMANISED ANTIBODIES DIRECTED AGAINST A33 ANTIGEN |
摘要 |
2128544 9413805 PCTABS00032 A33 antigen binding proteins are described for use in the diagnosis or treatment of colorectal tumours and metastases arising therefore. The binding protein may be a humanised A33 antibody, incl uding complete antibody molecules, fragments thereof, and, especially, multivalent monospecific proteins comprising two, three, four or more antibodies or fragments thereof bound to each other by a cross-linking agent. For diagnosis or therapy the humanised A33 antibody may be linked to a reporter or effector molecule.
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申请公布号 |
CA2128544(A1) |
申请公布日期 |
1994.06.23 |
申请号 |
CA19932128544 |
申请日期 |
1993.12.10 |
申请人 |
CELLTECH THERAPEUTICS LIMITED |
发明人 |
KING, DAVID JOHN;ADAIR, JOHN ROBERT;OWENS, RAYMOND JOHN |
分类号 |
G01N33/53;A61K39/395;C07D207/452;C07D403/14;C07K16/00;C07K16/30;C07K19/00;C12N1/21;C12N15/09;C12N15/13;C12P21/08;C12R1/91;G01N33/574;G01N33/577;(IPC1-7):C12N15/62;C12N15/28 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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