| 摘要 |
<p>The invention relates to recombinant retroviral vectors, derived from Moloney MuLV, carrying a suicide gene susceptible of transforming an inactive substance into a toxic substance for cells going through a division process, said vectors being characterized by the presence in their structure of LTR sequences from variants of MuLV, and having the properties: (a) of not being inactivated during passage through the carcino-embryonic or line germinal cells of mice; (b) the expression of the suicide gene kills only the cells in the course of division.</p> |
