发明名称 Harnstoff-Derivate.
摘要 Urea derivs. of formula (I), their hydrates and their pharmaceutically acceptable acid addn. salts are new, where R1 is piperidino or pyrrolidino, both opt. substd. by OH or 1-3C alkyl, A is ethylene, propylene orbut(en)ylene, R2 is 1-20C alkyl, 3-6C cycloalkyl, benzyl or phenyl opt. substd. by 1-3 of halo, 1-3C alkyl, 1-3C alkoxy, CF3, NH2, NO2 or OCH2O, and X is O or S. - Pref. R1 is piperidino or 4-hydroxy- or 4-methyl-piperidino, R2 is 1-6C alkyl or 3-6C cycloalkyl and A is propylene or butenylene. - N-(4-methoxyphenyl) -N'-(3-(3-piperidinomethyl phenoxy)propyl) urea is an example.
申请公布号 DE3886125(T2) 申请公布日期 1994.06.23
申请号 DE19883886125T 申请日期 1988.07.29
申请人 KYORIN PHARMACEUTICAL CO., LTD., TOKIO/TOKYO 发明人 MATSUKUBO, HIROSHI, OKAYA-SHI NAGANO-KEN;MATSUMOTO, TOYOMI, KAMIINA-GUN NAGANO-KEN;MIYASHITA, MITSUTOMO, NAGANO-KEN;OKAMURA, KYUYA, OHMIYA-SHI SAITAMA-KEN;TAGA, FUKUTARO, MINAMI-SAITAMA-GUN SAITAMA-KEN;SEKIGUCHI, HARUO, AGEO-SHI SAITAMA-KEN;HAMADA, KATSUHIRO, SHIMOTSUGA-GUN TOCHIGI-KEN
分类号 C07D295/08;A61K31/395;A61K31/40;A61K31/445;A61P1/04;A61P35/00;A61P43/00;C07D207/06;C07D207/08;C07D207/12;C07D211/10;C07D211/14;C07D211/46;C07D295/096 主分类号 C07D295/08
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