| 发明名称 |
MULTIVALENT SINGLE CHAIN ANTIBODIES |
| 摘要 |
The present invention discloses multivalent single chain antibodies which have two or more biologically active antigen binding sites. The multivalent single chain antibodies are formed by using a peptide linker to covalently link two or more single chain antibodies, each single chain antibody having a variable light domain linked to a variable heavy chain domain by a peptide linker.
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| 申请公布号 |
CA2117477(A1) |
申请公布日期 |
1994.06.23 |
| 申请号 |
CA19932117477 |
申请日期 |
1993.12.10 |
| 申请人 |
DOW CHEMICAL COMPANY (THE) |
发明人 |
MEZES, PETER S.;GOURLIE, BRIAN B. |
| 分类号 |
C12N15/09;A61K38/00;C07K16/00;C07K16/18;C07K16/30;C07K16/32;C07K16/42;C07K16/46;C07K19/00;C12N15/13;C12P21/08;C12R1/19;(IPC1-7):C12N15/62 |
主分类号 |
C12N15/09 |
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