| 摘要 |
<p>A33 antigen binding proteins are described for use in the diagnosis or treatment of colorectal tumours and metastases arising therefore. The binding protein may be a humanised A33 antibody, incl uding complete antibody molecules, fragments thereof, and, especially, multivalent monospecific proteins comprising two, three, four or more antibodies or fragments thereof bound to each other by a cross-linking agent. For diagnosis or therapy the humanised A33 antibody may be linked to a reporter or effector molecule.</p> |
