摘要 |
A reagent for the identification or purification of a serine esterase enzyme comprising an organophosphorus serine esterase inhibitor to which is bonded a reporter group. Particularly preferred is a compound of formula (II), where R<1> is hydrogen, or an alkyl, aryl, alkoxy, acyl, halogen or nitro group or a fused aromatic ring; B-R<2> is C = O or CHR<2> where R<2> is hydrogen or an alkyl, aryl or cyano group; X is O, S, NH or NR; A is a reporter group. |