发明名称 |
Anti-feline herpesvirus-1 recombinant antibody and gene fragment coding for said antibody |
摘要 |
An anti-feline herpesvirus-1 recombinant antibody which is efficacious in treating, preventing and diagnosing feline herpesvirus-1 (FHV-1) infection, and a gene fragment useful for the preparation of the antibody. A gene fragment coding for the antibody V region bearing an FHV-1 specific avidity of a mouse monoclonal antibody having an excellent activity of neutralizing FHV-1 is obtained by constructing cells which produce the antibody. A chimeric anti-FHV-1 recombinant antibody is prepared from the above gene fragment and another gene fragment coding for a feline antibody C region. <IMAGE> |
申请公布号 |
AU5596194(A) |
申请公布日期 |
1994.06.22 |
申请号 |
AU19940055961 |
申请日期 |
1993.11.25 |
申请人 |
JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTIT |
发明人 |
KAZUHIKO KIMACHI;HIROAKI MAEDA;KIYOTO NISHIYAMA;SACHIO TOKIYOSHI |
分类号 |
A61K39/395;A61K38/00;A61P31/12;C07K14/00;C07K14/03;C07K16/00;C07K16/08;C12N15/02;C12N15/09;C12N15/13;C12P21/08;C12R1/91 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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