4-methylthiazole derivatives, their methods of preparation and the pharmaceutical compositions in which they are present

摘要

PCT No. PCT/FR91/00118 Sec. 371 Date Oct. 19, 1992 Sec. 102(e) Date Oct. 19, 1992 PCT Filed Feb. 14, 1991 PCT Pub. No. WO91/12246 PCT Pub. Date Aug. 22, 1991.The present invention relates to novel 4-methylthiazole derivatives, to their methods of preparation and to the pharmaceutical compositions in which they are present. According to the invention, these derivatives have the general formula <IMAGE> (I) in which n is equal to 0 or 1 and R1 and R2, which are identical or different, are selected from a hydrogen atom, a halogen, a hydroxyl group, a trifluoromethyl group, an alkyl group having from 1 to 4 carbon atoms and an alkoxy group having from 1 to 5 carbon atoms and are useful in the treatment of cardiovascular diseases associated with hyperactivity of the sympathetic nervous system.