发明名称 |
TRANSDERMAL THERAPEUTICAL SYSTEM CONTAINING FIZOSTIGMINE AND PREPARATION THE SAME |
摘要 |
PCT No. PCT/EP93/02970 Sec. 371 Date Jul. 12, 1995 Sec. 102(e) Date Jul. 12, 1995 PCT Filed Oct. 27, 1993 PCT Pub. No. WO94/10999 PCT Pub. Date May 26, 1994A transdermal therapeutic system for the administration of physostigmine to the skin, consisting of a backing layer impermeable to active substance, a pressure-sensitive reservoir layer containing 40 to 90%-wt. polymeric material and 0.1 to 20%-wt. physostigmine base or one of the pharmaceutically acceptable salts thereof, and of a detachable protective layer covering the reservoir layer, comprises in its reservoir layer acrylate- and/or methacrylate-based polymeric material and 0.1 to 40%-wt. of a softener containing the hydroxyl group with an HLB value between 1.1 and 12.0. |
申请公布号 |
LTIP1469(A) |
申请公布日期 |
1994.06.15 |
申请号 |
LTIP1469 |
申请日期 |
1993.11.12 |
申请人 |
LTS LOHMANN THERAPIE-SYSTEME GMBH & CO. KG |
发明人 |
DEURER,LOTHAR;HILLE,THOMAS;PROFITLICH,THOMAS;STANISLAUS,FRITZ;WALTER,KERSTEN |
分类号 |
A61L15/44;A61K9/70;A61K31/40;A61K31/405;A61K31/407;A61K47/10;A61P25/00;A61P25/28 |
主分类号 |
A61L15/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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