| 发明名称 |
PEPTIDE CORRESPONDING TO CD44 EXON 6, ANTIBODIES SPECIFIC FOR SAID PEPTIDE AND USE OF THESE ANTIBODIES FOR DIAGNOSIS OF TUMORS |
| 摘要 |
2149635 9412631 PCTABS00032 There is marked over-expression of multiple spliced variants of the CD44 gene in tumour compared to counterpart normal tissue. This observation forms the basis of a method of diagnosing neoplasia by analysis of a sample of body tissue or body fluid or waste product. A new exon 6 of 129bp has been located and sequenced. Antibodies specific to the exon have been prepared and are claimed as new compounds suitable for use in the detection of CD44 proteins and for the in vivo imaging and therapy of tumours.
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| 申请公布号 |
CA2149635(A1) |
申请公布日期 |
1994.06.09 |
| 申请号 |
CA19932149635 |
申请日期 |
1993.11.22 |
| 申请人 |
ISIS INNOVATION LIMITED |
发明人 |
TARIN, DAVID;MATSUMURA, YASUHIRO |
| 分类号 |
G01N33/53;A61K38/00;A61K39/00;A61K39/395;A61K49/00;A61P35/00;C07K14/16;C07K14/705;C07K16/28;C07K19/00;C12N5/10;C12N15/02;C12N15/06;C12N15/09;C12P21/08;C12R1/91;G01N33/574;G01N33/577;(IPC1-7):C12N15/62;C07K7/06;C07K7/08;A61K51/10;C12N15/12;C07K16/30;A61K47/48 |
主分类号 |
G01N33/53 |
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