| 摘要 |
<p>Method of treating 5-HT3-mediated disorders, which comprises systemic administration of an effective amount of a compound of formula (I), the pharmaceutically acceptable acid addition salt forms and the stereochemically isomeric forms thereof, wherein R?1 and R2¿ represent hydrogen, or R?1 and R2¿ taken together form a bivalent radical of formula (a): -CH = CH-CH = CH-, (b): -CH = C(Cl)-CH = CH- or (c): -CH = CH-C(Cl) = CH-; n represents 2, 3 or 4; R3 represents hydrogen or methoxy; m represents 1 or 2; R4 represents hydrogen, amino or C¿1-3?-alkylcarbonylamino; and R?5¿ represents hydrogen or halo; novel compounds; compositions; processes for preparing novel compounds and intermediates.</p> |
