发明名称 INJECTABLE COMPOSITION
摘要 A composition of taxol and polyethoxylated castor oil is pH balanced to have a pH less than 8.1 to improve stability. This composition can include an acid, preferably citric acid, to adjust the pH value. The invention includes a method of formulating a taxol solution for injection by mixing an acid with a carrier material, such as castor oil, to form a carrier solution after which taxol is mixed with the carrier solution to form the taxol solution at a pH of less than 8.1.
申请公布号 WO9412030(A1) 申请公布日期 1994.06.09
申请号 WO1993US11199 申请日期 1993.11.18
申请人 NAPRO BIOTHERAPEUTICS, INC. 发明人 CARVER, DAVID, R.;PROUT, TIMOTHY, R.;EWALD, HERNITA
分类号 C07D305/14;A01D43/02;A01N43/02;A61J1/00;A61K9/00;A61K9/08;A61K31/335;A61K31/337;A61K47/02;A61K47/10;A61K47/12;A61K47/14;A61K47/44;(IPC1-7):A01N43/02 主分类号 C07D305/14
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