PROTEIN LABEL AND DRUG DELIVERY SYSTEM

摘要

PROTEIN LABEL AND DRUG DELIVERY SYSTEM A bridging molecule carrying a drug, or a label such as a fluorophore, which adds across disulfide bonds of molecules, particularly proteins, and methods of manufacturing and using the bridging molecules, are disclosed. The bridging molecule is reactive with sulfhydryl groups formed by the reduction of disulfide bonds of the protein. The functional groups of the bridging molecules are typically -SH groups.