发明名称 NEW MEDICAL COMPOSITION CONTAINING ESTER OF OMEGA-3 POLYUNSATURATED FATTY ACID AND USE OF THE SAME FOR LOCAL TREATMENT OF DISEASE
摘要 PURPOSE: To medicinal composition useful of the treatment of psoriasis, phlebitis, atopic dermatitis, etc., which contains, as an active ingredient, ester of anω-3 polyunsaturated aliphatic acid, and has ability to avid the evolution of unpleasant and undesirable odor. CONSTITUTION: The composition contains, as an active ingredient, 10-40 wt.% of a 1-3C alkyl ester of anω-3polyunsaturated aliphatic acid (e.g. ethyl ester of cis-5,8,11,14,17-eicosapentaenoic acid). Further, preferably, the composition contains 0.3-5 wt.%, based on the ester, of antioxidant derived from phenol (e.g. a butylated hydroxyanisole) and 1-20 wt.%, based on the ester, of triehtyl citrate. Addition of the antioxidant into the composition prevents the decomposition of the ester and thus inhibits the evolution of unpleasant and undesirable odor. Activity of the antioxidant is increased by the addition of the triethyl citrate.
申请公布号 JPH06157351(A) 申请公布日期 1994.06.03
申请号 JP19930219182 申请日期 1993.08.11
申请人 PUROSUPA BV 发明人 CHIBERIO BURUTSUTSUSE;JIIOBUANI MOTSUCHI;REMO RATSUJIERI
分类号 A61K8/34;A61K8/37;A61K8/67;A61K9/70;A61K31/20;A61K31/23;A61K47/10;A61K47/14;A61K47/22;A61P17/00;A61Q15/00;(IPC1-7):A61K47/10 主分类号 A61K8/34
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